How to Select a Lab Freezer or Refrigerator

How to Choose a Lab Refrigerator or Freezer

Lab freezers and lab refrigerators have received increasing attention in the press because of their importance is storing vaccines between the time of manufacture and being injected into a patient’s arm.  As reported in Scientific American, lab freezers and lab refrigerators play a role in the “COVID Cold Chain.”  This post explains how to select a lab freezer or refrigerator for coronavirus vaccines and other temperature-critical products.

The Difference Between Lab Units and Household Units

A lab freezer or refrigerator is designed and constructed to meet much stricter standards than typically found in household or commercial units.  Vaccines, other pharmaceuticals, blood and plasma, for example, must be stored within tight temperature ranges to avoid loss of potency or spoilage. 

Important Points to Keep in Mind

Proper storage of these and other temperature-sensitive products is strictly governed  by organizations such as the Food and Drug Administration (FDA) and agencies such … Read the rest

Guide to CDC Recommended Laboratory and Medical Refrigerators and Freezers for Vaccine Storage

Vaccine Storage

CDC Recommendations for Approved Laboratory, Medical, and Biomedical Refrigerators and Freezers for Vaccine Storage

Maintaining a cold chain through-out the entire vaccine supply chain is critical to the safety and security of vaccines. According to the CDC, the cold chain begins with the cold storage unit at the manufacturing plant, extends to the transport and delivery of the vaccine and proper storage at the provider facility, and ends with the  administration of the vaccine to the patient.

Additionally, the CDC stresses in its Vaccine Storage and Handling Pink Book that manufacturers, distributors, public health staff, and health care providers share responsibility to ensure the vaccine cold chain is maintained from the time vaccines are manufactured until they are administered.

To ensure safe vaccine storage, medical grade laboratory, pharmacy, and biomedical refrigerators and freezers must comply with … Read the rest

CDC Refrigeration Guidelines for Submitting COVID-19 Specimens for Testing

Plan for COVID-19 Vaccine Storage

While the search for a Coronavirus vaccine proceeds at full throttle a crucial issue is proper collection, labeling, storage and shipping of COVID-19 specimens to CDC laboratories for testing. Among procedures spelled out in the CDC’s Interim Guidelines is that coronavirus specimen shipments must be stored at 2-8⁰C and shipped overnight on icepack for testing within 72 hours. If a delay in shipping is expected, specimens must be stored at -70⁰C or lower. These agree with a companion guideline for post-mortem testing

Temperature Guidelines for COVID-19 Test Kits

Because there are so many sites collecting specimens there is a national shortage of reagents for the tests. Test kits are available for real-time PCR and in vitro diagnostic procedures.  One manufacturer specifies storage temperatures from -10⁰ to -30⁰C down to ≤-70⁰C depending on the components of the kits.

To meet these storage requirements you should be familiar with

  • Scientific Refrigerators
  • Scientific Freezers
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How to Specify a Compact Medical Refrigerator

How to Specify a Compact Medical Refrigerator

Health care clinics must exercise care when selecting a compact medical refrigerator to store temperature-sensitive products such as vaccines and other pharmaceuticals.  A compact medical refrigerator is a smart choice when space is at a premium, but a small size should not be at the cost of critical features that protect contents.  This post provides tips on how to specify a compact medical refrigerator.

Why a Medical Refrigerator is Important

If there is temptation to buy a dormitory or residential-grade refrigerator it must be resisted.  In fact, the former is definitely ruled against in the CDC’s Vaccine Storage and Handling Toolkit while the latter may be acceptable under certain conditions.  We encourage you to download and review these guidelines, updated for 2020 before you decide on your medical refrigerator.

Especially important is compliance with CDC and Vaccines for Children refrigeration guidelines if your healthcare facility participates in these programs. 

The “Cost”

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Specify a Pass-Through Industrial Refrigerator

How to Specify a Pass-Through Industrial Refrigerator

Pass through industrial refrigerators are preferred cold-storage units for applications where convenience and/or content protection is desired when transferring contents between one location and another.  As the name suggests these refrigerators allow access from the front and back for stocking and removal of their contents.  In this post we describe to buyers important tips on how to specify a pass-through industrial refrigerator.

But first…….

Do you Need a Pass-Through Industrial Refrigerator?

In many instances they can simplify handling and storage and enhance workflow. 

For example, in a typical scenario a pass-through refrigerator is used to permit products to be stocked from the back and removed from the front.  This feature supports a “first-in-first-out” inventory control system as stockers move the older product forward to minimize loss due to expiration or use-by  dates. 

Pass-through refrigerators can also serve as a temperature-controlled “boundary” between separate facility functions such as separating a clean … Read the rest

How to Safely Store Vaccines for the 2019-2020 Flu Season

How to Safely Store Vaccines for the Flu Season

With the 2019-2020 flu season upon us it’s time for healthcare facilities to take a close look at their refrigeration equipment for vaccine storage and temperature monitoring.  The CDC has published detailed recommendations on how to safely store vaccines in their Vaccine Storage and Handling Toolkit available online.  This post summarizes their recommendations on how to  safely store vaccines for the 2019-2020 flu season. 

A  Summary of the 2018-2019 Flu Season

The Centers for Disease Control and Prevention notes that as many as 42.9 million cases of influenza were reported from Oct. 1, 2018 to May 4, 2019 resulting in 20.1 million medical visits and 647,000 hospitalizations.  At this posting no estimates have been made for the 2019-2020 … Read the rest

How Scientific Refrigeration Equipment Works

Norlake White Diamond Refrigerators and Freezers

Scientific refrigerators, also called pharmaceutical refrigerators or lab refrigerators, meet stringent requirements essential to protect contents from temperature fluctuations above or below those recommended by content manufacturers.  Residential-type refrigerators do not make the grade.  Reasons described in this post will help you understand how scientific refrigerators work.  

How Scientific Refrigeration Equipment Makes Cold

The first thing you need know is that when a liquid evaporates it absorbs heat and when a gas condenses to a liquid it releases heat.  Got that?  Good. 

Let’s start with the receiver where the liquid refrigerant is stored under high pressure.  The liquid passes through a thermal expansion valve causing a … Read the rest

Norlake White Diamond Feature-Rich Line of Undercounter/Freestanding Refrigerators and Freezers

Norlake White Diamond Refrigerators and Freezers

To select the correct undercounter/freestanding lab refrigeration system from the Norlake White Diamond series for a small to medium-sized laboratory or healthcare facility you must evaluate a system’s capability to satisfy a number of important criteria.  This post explains important criteria to consider.  They include:

  • required storage capacity
  • refrigerator/freezer temperature range
  • stable, accurate temperature control
  • alarm systems signaling temperature excursions
  • auto defrost vs. manual defrost
  • compliance with standards
  • other useful features

While these criteria apply to any laboratory/scientific refrigeration system, our post focuses on undercounter/freestanding refrigerators and freezers for small to medium-sized facilities.  Our examples come from the new line of Norlake White Diamond units now available from Tovatech.

Determine Optimum Storage Capacity

Norlake White Diamond Freezer/RefrigeratorLab and scientific refrigerators and freezers, as with domestic models used in your home, are available in a wide range of storage capacities.  Two things to keep in mind about storage capacity when selecting your unit:

  1. Refrigerators
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How to Choose Manual or Auto-Defrost Cold Storage Units for the Lab

Lab refrigerators and lab freezers come in various sizes and temperature capabilities, many of which are designed for specific storage functions.  What you store in these units has a large part in determining the type of unit you purchase.  This post will cover decision-making factors such as storage temperature capability and whether manual or auto-defrost equipment should be specified when you choose manual or auto-defrost cold storage units for the lab.

We’ll separately take a look at scientific refrigerators and scientific freezers, then provide suggestions on how to manage defrosting operations.

Always keep in mind that temperature monitoring and alarming is a subject onto itself in laboratory refrigerators and freezers.  The defrosting operation by definition signals a change in storage temperature within these units, whether a scientific freezer or scientific refrigerator.  We’ll touch on this briefly at the end of our post.

In addition, two important points to include in … Read the rest

How to Select a Stability Test Chamber

Knowing how to specify a stability test chamber calls for a clear understanding of what stability test chambers do, how they relate to the various components or ingredients that go into the product you manufacture and where these products are used. 

In this post we’ll provide some examples of things to consider when specifying a stability test chamber then share suggestions on what to look for in this critical equipment. 

As a refresher or for readers new to the subject here is an answer to what constitutes a stability test chamber.

What is a Stability Test Chamber?

Most stability test chambers resemble a large scientific refrigerator.  Only instead of keeping contents cool, their function is to replicate variations in temperature, humidity and light over long periods of time. This is critical when pharmaceutical companies, for example, wish to bring new products to market. 

It has everything to do with … Read the rest