Lab freezers and lab refrigerators have received increasing attention in the press because of their importance is storing vaccines between the time of manufacture and being injected into a patient’s arm. As reported in Scientific American, lab freezers and lab refrigerators play a role in the “COVID Cold Chain.” This post explains how to select a lab freezer or refrigerator for coronavirus vaccines and other temperature-critical products.
The Difference Between Lab Units and Household Units
A lab freezer or refrigerator is designed and constructed to meet much stricter standards than typically found in household or commercial units. Vaccines, other pharmaceuticals, blood and plasma, for example, must be stored within tight temperature ranges to avoid loss of potency or spoilage.
Important Points to Keep in Mind
Proper storage of these and other temperature-sensitive products is strictly governed by organizations such as the Food and Drug Administration (FDA) and agencies such … Read the rest
The ultrasonic cleaner solution you select plays a major role in successful ultrasonic cleaning operations. Ultrasonic cleaner solutions are available in a wide variety of formulations – each designed for specific cleaning tasks. These solutions are also referred to as cleaning chemistries and in some cases “soaps.” We’ll stick with ultrasonic cleaner solution in this post and provide you with tips on how to make the right selection.
How an Ultrasonic Cleaner Solution Works
Regardless of the chemistry, an ultrasonic cleaner solution works by a process called cavitation. This is defined as the implosion of millions of microscopic vacuum bubbles in an ultrasonic cleaner’s tank filled with the solution. Bubbles are created by generator-powered transducers vibrating at ultrasonic frequencies such as 37,000 cycles per second (37 kHz).
When bubbles contact products to be cleaned they implode violently (but safely) against all wetted surfaces to blast loose and carry away contaminants.
Further details … Read the rest
An earlier Tovatech post on selecting an ultrasonic cleaner noted that the ultrasonic cleaner market is “expected to grow from USD 1.6 billion in 2019 to USD 2.2 billion by 2024, at a CAGR of 6.5%.” Much of this growth is due to the many ultrasonic cleaner uses that have evolved over the years.
In this post we provide you with an overview of selected ultrasonic cleaner uses starting with a brief discussion of the ultrasonic cleaner process and why it works so well.
A Brief on the Ultrasonic Cleaner Process
Ultrasonic cleaners use the power of cavitation – the violent implosion of billions of microscopic bubbles – to remove contaminants from any surface that can be safely immersed in biodegradable cleaning solutions formulated for specific cleaning tasks.
Ultrasonic cavitation is created in an ultrasonic cleaner tank by generator-powered ultrasonic transducers bonded to the tank bottom.
Vibrating at ultrasonic … Read the rest
PubChem, an open chemistry database at the National Institutes of Health (NIH), defines acetone as a colorless, volatile, flammable organic solvent. It is also called dimethyl ketone, 2-propanone, and beta-ketopropane. As a low flash point solvent, acetone cleaner is widely used in manufacturing as a highly effective degreaser for residue-free removal of contaminants in an ultrasonic bath.
Key cautions or “red alerts” for using an acetone cleaner include low flash point, volatility and flammability. This is why special precautions are required to safely use acetone cleaner in an ultrasonic bath to avoid potential fire and an explosion. Here we describe equipment and procedures to follow when using acetone cleaner in an ultrasonic bath.… Read the rest
In its “Guideline for Disinfection and Sterilization in Healthcare Facilities” the CDC notes “Ultrasonic cleaning removes soil by cavitation and implosion in which waves of acoustic energy are propagated in aqueous solutions to disrupt the bonds that hold particulate matter to surfaces.”
Sub-par performance of a medical ultrasonic cleaner could lead to trouble. That’s because a number of factors can compromise the efficiency of these cleaners, leaving contaminants that might not be revealed by visual examination. This is especially relevant when medical instruments and labware have complex, difficult-to clean configurations. OK-Sonic™ medical ultrasonic cleaner performance validation strips provide added assurance that your ultrasonic cleaner is doing its job. … Read the rest
An ultrasonic cleaner machine is often first choice for cleaning or processing operations across a broad spectrum of industry. This is borne out by a comprehensive marketsandmarkets report predicting that the market is “expected to grow from USD 1.6 billion in 2019 to USD 2.2 billion by 2024, at a CAGR of 6.5% during the forecast period.”
Why is this?
Ultrasonic cleaner machines are unsurpassed when it comes to removing contaminants from virtually any hard surface that can be safely immersed in a cleaning solution.
They are also widely used in the pharmaceutical and other processing industries as sonicator baths because of their ability to disperse, mix and dissolve samples.
The challenge is specifying your ultrasonic cleaner; its accessories, cleaning solution formulations, and cleaning procedures to accomplish tasks in the most efficient manner.
Which is the purpose of this post. But before digging into the 10 things you should know, … Read the rest
Fuel injection systems have replaced the carburetor but a Gili’s Automotive post states “While carburetors may not have a life in new vehicles today, chances are good that they’ll still be used for many years to come.” That’s because “Carburetors, unlike fuel injection systems, are relatively straightforward when it comes to repairing them. Fuel injection requires sophisticated computers, but carburetors require only a screwdriver and a willingness to get one’s hands dirty.” Keeping carburetors clean is easy with an ultrasonic cleaner.
At this posting Phase 3 clinical trials are underway for COVID-19 vaccines, some of which call for an ultra-low freezer for storage and transport. Examples described in a September Wall Street Journal article notes the unusually cold storage temperatures – as low as -80⁰C – required. Covid-19 vaccine candidates are one of many applications for ultra-low freezers. This post provides you with info on when and how to specify one of these units.
Unlike “ordinary” freezers, ultra-low freezers are not inexpensive. The investment is important when the job is to protect contents of high value and sometimes for long periods of time. More on this below.
Fortunately there are a number of ultra-low freezers on the market to ease the selection of a model that best suits your needs.
What is Meant by Ultra-Low Freezers?
There are freezers, low-temperature freezers and ultra-low … Read the rest
Challenges relating to cleaning new or refurbished parts, many of which require subsequent processing such as painting and plating, are increasing due to environmental regulations. This post shows you why an ultrasonic parts cleaner using eco-friendly biodegradable parts cleaning solutions is a favored alternate to washing and spraying with harsh solvents along with their associated disposal concerns.
Why Choose an Ultrasonic Parts Cleaner?
Let’s start with why you should consider an ultrasonic parts cleaner.
Cleaning is faster, safer and easier when using an ultrasonic parts cleaner. Machining oils, grease, residues left from molding or handling, soot and other contamination are difficult and can be dangerous to remove by soaking in harsh and sometimes flammable solvents, manually scrubbing or power washing in solvent parts washers.
Moreover these methods do not reach difficult-to-access surfaces such as cracks, crevices, small diameter and blind holes where contaminants remain and can cause future problems.… Read the rest
A question posed in the September 5-6, 2020, Wall Street Journal asks “do we have enough freezers?” This relates to the unusually cold storage temperatures – as low as -80⁰C – recommended by certain producers of Covid-19 vaccine candidates in Phase 3 clinical trials.
Proper vaccine storage temperatures have always been a concern as evidenced by the CDC’s continually updating its Vaccine Storage and Handling Toolkit. The Toolkit details stringent recommendations relating to critical considerations such as staffing and training for safe handling, storage and temperature monitoring, inventory management, transport, and emergency vaccine and storage handling.
Earlier, MarketWatch identified Moderna, BioNTech and Pfizer as examples of Covid-19 candidates requiring low temperatures (-20⁰C Moderna) and -70⁰C (BioNTech and Pfizer). Other candidates are J&J Janssen and AstraZenca at between 0⁰ and -10⁰C. In total, some 9 firms have advanced to Phase 3 trials as reported in a Wall Street Journal September … Read the rest