What you’ll learn in this digital HPLC flowmeters overview:
- What flow meters do
- Flow measurement validation options
- HPLC flow meter calibration
- Mounting options for HPLC flow meters
- Connecting the flow meter to a PC
- How to maintain an HPLC flowmeter
- User testimonials
Flow meters come in many sizes and find application in a wide range of industries. As examples they meter gasoline pumped into your car and fuel oil into your heating system’s tank. But instead of metering in gallons (for example) digital HPLC Flowmeters measure small flow rates such as 0.05 to 25 milliliters (mL) per minute. This post provides an overview of lightweight, portable, and exceedingly accurate digital High Performance Liquid Chromatography (HPLC) flowmeters.
What HPLC Flow Meters Do
Among functions performed by HPLC are included checks for purity, monitoring changes in pharmaceutical intermediates during chemical synthesis scale-up, stability and dissolution tests, and performing ongoing quality control procedures.… Read the rest
Your investment in an ultrasonic cleaner pays dividends in terms of faster, more thorough cleaning enabling you to increase throughput in your business and, we hope, improve your profitability. In this post we describe how ultrasonic cleaner parts such as baskets and accessories contribute to your bottom line.
Overview of Ultrasonic Cleaner Parts
The objectives of your ultrasonic cleaning operations governs the parts you should have to accomplish the tasks. Here’s what we’ll cover in this overview:
- Baskets – do you need them and why?
- Alternatives to baskets
- Controlling noise and evaporation
- Managing cleaning solution temperatures
- Cleaning with highly acidic solutions
- Cleaning with volatile solvents
- Sample prep with an ultrasonic cleaner
Why Use a Basket for Ultrasonic Cleaning?
Cleaning baskets may be an optional accessory when buying an ultrasonic cleaner. That’s because many users may already have baskets. Ultrasonic cleaner parts baskets are needed for two major reasons:
L3 Harris EDD (Electron Devices), Torrance, CA, manufactures products such as traveling wave tubes, xenon ion propulsion systems, electronic power conditioners and microwave power modules for a variety of space and defense applications. “Solvent ultrasonic cleaning is used to remove machining oils and particulates from piece parts and brazed assemblies at various stages of the assembly process including preparing surfaces for a subsequent coating,” says Cathy Barnes, the company’s Senior Materials and Process Engineer.
Explosion Proof Ultrasonic Cleaners Meet Strict Safety Standards
“While ultrasonic cleaning using volatile solvents yields outstanding cleaning results, cleaning with low flash point flammable solvents requires extreme caution including compliance with National Electric Code (NEC), National Fire Protection Association (NFPA), our plant safety personnel and local fire regulations,” Ms. Barnes says. “For compliance our Torrance facility uses two SOL XP explosion-proof ultrasonic cleaners supplied by Tovatech.”
The 6-gallon capacity SOL XP units operate at 40 … Read the rest
A large ultrasonic cleaner is a close cousin to an industrial ultrasonic cleaner but is selected to clean (you guessed it!) large parts. Or a large number of parts in the same cycle. An obvious characteristic of large ultrasonic cleaners is cleaning tank dimensions (and therefore cleaning solution capacity) to accommodate the parts, either in size or number, that you need to clean. We invite you to read this post for other important considerations in selecting a large ultrasonic cleaner.
Industrial ultrasonic cleaners come in many sizes, shapes and features. This guide will help you pick the equipment right for you.
What is an “Industrial” Ultrasonic Cleaner?
You might think an industrial ultrasonic cleaner must be “big” because it is handling industrial products. Not necessarily so. Your industrial parts washer size (or cleaning solution capacity) is governed by the size of parts you are cleaning. They are offered as benchtop and floor mounted models.
Another consideration to keep in mind is the duration of your cleaning cycles. Long-term cleaning cycles (i.e. operating continuously over a work shift) mean your unit should have a heavy-duty tank to prolong service life.
In Ultrasonic Cleaning, an Historical Perspective, author Timothy J. Mason notes “The development of ultrasonic cleaning dates from the middle of the 20th century and has become a method of choice for a range of surface cleaning operations.” This helps explain why, according to a Fortune Business Insights report, “the global ultrasonic cleaning equipment market was $604.8 million and projected to reach $783.1 million by 2027.”
The Basics of Ultrasonic Cleaning
A way to describe how ultrasonic cleaners work is likening them to an automatic dishwasher, but with some added refinements. An automatic dishwasher, much the same as an ultrasonic cleaner, combines water and a detergent to remove grease, grime and other contaminants from objects being cleaned.
But instead of cleaning pots and pans and … Read the rest
Precision and accuracy are two critical words (but with different meanings*) in pharmaceutical, food processing and other industries that come under continuous scrutiny by the FDA, the Code of Federal Regulations Title 21 and other standards. In brief IQ, OQ and PQ mean Installation Qualification, Operational Qualification and Performance (or Process) Qualification. The letter V for verification can be used in place Q.
But we promised a PDQ explanation, so let’s take a quick look at IQ, OQ and PQ.
The Purpose of IQ, OQ and PQ
A purpose of IQ, OQ and PQ is ensuring that sensitive laboratory and processing equipment meet strict standards as those mentioned above. An example of such equipment is an HPLC system, including its pumps. These systems must precisely and accurately analyze pharmaceutical compounds as they proceed from R&D into manufacturing. More simply stated IQ, OQ and PQ mean that equipment performs “as … Read the rest
Elma – the specialists for ultrasonic technology work in close cooperation with the customers to develop new ultrasonic cleaning processes for laboratory applications, such as analyzing, sample processing and cleaning of laboratory instruments. The range of our ultrasonic units is optimized for use in laboratories. The Elma units are indispensable both for research and for the practical use in the lab to find solutions for problems and to get reproducible test results.
Elma offers various different types of ultrasonic cleaners. Each series consists of units of different sizes. They are designed for special applications and meet the requirements of the everyday work in a lab.
Practical accessories facilitate the handling, and specialized additional equipment expand the range of possible applications, e.g. for sieve cleaning.
The cleaning of laboratory glassware and laboratory instruments is a crucial task in any lab. Elma offers a family of chemical cleaners which can be used … Read the rest
Calibration weights for digital scales are key elements to ensure, in the simplest sense, that you get what you pay for. For many of us this is exemplified by visits to the deli counter in the supermarket. We want assurance that the weight shown on the scale is accurate. The U.S. Government’s Weights and Measures Division sets the guidelines. Here we describe the role of calibration weights for digital scales in keeping scales accurate.
Why Digital Scale Calibration is Important
Granted, we all want assurances that the weight displayed by a scale is accurate.
But it does not take much to throw off the accuracy of a digital scale. We cover this in our post on weighing accuracy. While that post focuses on analytical balances, the importance of calibrating digital scales is no less important.
It is absolutely … Read the rest
How Can I Use Flammable Solvents in an Ultrasonic Cleaner?
Examples of a widely used flammable solvents are IPA (Isopropyl alcohol), Acetone, and IMS (Industrial Methylated Spirits). Any time flammable solvents are used for cleaning purposes there is risk of fire or explosion due to ignition of volatile vapors by a flash source. Ignition can occur from any source due to spills or as flammable solvent vapors spread. This guide will explain how you can safely use flammable solvents in an ultrasonic cleaner.
You may not have to use a flammable solvent as your cleaning solution. Watch the video below for details on selection a cleaning solution for your ultrasonic cleaner.
Cleaning with flammable solvents requires extreme caution in any case but ultrasonic cleaning with … Read the rest