How a HPLC Digital Flow Meter Works

FlowCal 5000 Digital HPLC Flow Meter

Before explaining how a HPLC digital flow meter works  here’s an explanation of what digital flow meters do: 

Digital flowmeters performing  high performance liquid chromatography are used to measure the accuracy of HPLC pumping systems in order to meet FDA and other regulations regarding installation qualification (IQ), operational qualification (OQ) and performance qualification (PQ) of equipment used in the pharmaceutical and biopharmaceutical industries as well as other analytical labs.

The process demands accurate, reproducible column retention time as an analyte (what is being analyzed) is pumped through the HPLC system.

These precision digital flow meters are not to be likened to flow meters used on process lines measuring flow rates in, for example, thousands of gallons per minute but instead in fractions of milliliters per minute. … Read the rest